Product Information

METANX FC™ 180ct bottle on a white background

Metanx FC™

Our original formula, prescribed to help optimize nutrient balance in patients with peripheral neuropathy, helps support nerve repair and recovery and helps protect against further nerve damage.

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Ingredients

Each capsule contains 3mg of L-Methylfolate Calcium (as Metafolin®), 35mg of Pyridoxal-5-Phosphate and 2mg of Methylcobalamin.

Microcrystalline Cellulose and Silicon Dioxide, Vegetarian Capsule (Hypromellose, Carrageenan, Potassium Acetate, Black Iron Oxide, Hydroxypropyl Cellulose), Pyridoxal-5-Phosphate, L-Methylfolate Calcium, Methylcobalamin, Magnesium Stearate.

Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.

Directions & Dosage

Adults take one capsule twice daily or two capsules once daily or as directed by your healthcare provider.

Available in 90-count (45-day supply) and 180-count (90-day supply).

Questions: 866-331-6440

Warnings & Storage

Keep out of reach of children.

Store at controlled room temperature 59°F to 86°F (15°C to 30°C). Protect from heat, light, and moisture.

METANX Pro Nerve Health™ 180 ct bottle on a white background

MetanxPRO Nerve Health™

This formula adds acetyl-L-carnitine (ALC) to aid in mitochondrial energy production. Clinical studies on ALC report reduction in peripheral nerve discomfort—like burning or deep-aching pain—in as little as 14 days.1
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Ingredients

Each capsule contains 3mg of L-Methylfolate Calcium (as Metafolin®), 35mg of Pyridoxal-5-Phosphate, 2mg of Methylcobalamin and 500mg of Acetyl-L-Carnitine.

Acetyl-L-Carnitine HCl, Vegetarian Capsule (Hypromellose, Black Iron Oxide), Microcrystalline Cellulose, Pyridoxal-5-Phosphate (Vitamin B6), Silicon Dioxide, Magnesium Stearate (Vegetable Source), L-Methylfolate Calcium, Methylcobalamin (Vitamin B12).

Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.
Directions & Dosage

Adults take one capsule twice daily or two capsules once daily or as directed by your healthcare provider.

For use only under medical supervision.

Available in 90-count (45-day supply) and 180-count (90-day supply).

Questions: 1-844-639-9726 (M-F 8am to 5pm ET)

Warnings & Storage

Keep out of reach of children. If you are pregnant or nursing, consult with your healthcare provider.

Store at controlled room temperature 59°F to 86°F (15°C to 30°C). Protect from heat, light, and moisture.

Physician examining a patient's foot with anatomical models in the background

Clinical Impact of Metanx® Ingredients

Collectively, the bioactive ingredients in Metanx® have been shown over time to help:

  • ✓ Increase vascular blood flow - by stimulating nitric oxide synthesis12,35
  • ✓ Repair nerve structure - by stimulating remyelination, leading to functional restoration.15,22,34
  • ✓ Restore nerve function & sensation - in peripheral limbs.15,34,62
  • ✓ Protect against further nerve damage - by reducing oxidative stress & pro-inflammatory markers.16,22,30-33
  • ✓ Reduce nerve discomfort and pain associated with PN - by downregulating glutamate release to modulate pain response.16,17

Bioactive Nutrients in Metanx® that Target PN Mechanism

01. L Methylfolate/folate
Illustration of nerve growth factor and L-methylfolate with a focus on nerve repair

L-Methylfolate/folate

  • L-methylfolate stimulates NO synthesis, which increases vascular blood flow12, 35
  • L-methylfolate via NO enhances nerve growth factor effect35
    • 02. Pyridoxal 5'-phosphate
    Neuron with a close-up of AGEs and pyridoxal 5'-phosphate on a white background

    Pyridoxal 5'-phosphate

  • Pyridoxal 5'-phosphate inhibits formation of AGEs that are damaging to peripheral nerves32
    • 03. Methylcobalamin
    Illustration of a neuron with a close-up of methylcobalamin and nerve regeneration.

    Methylcobalamin

  • Methylcobalamin stimulates myelination and promotes nerve regeneration.15
    • 04. Acetyl-L-carnitine
    Diagram of a neuron with a focus on acetyl-L-carnitine and mitochondrial function.

    Acetyl-L-carnitine

  • Acetyl-L-carnitine enhances neuronal energy supply & axonal regeneration and supports nerve discomfort in PN.63

    • Potential to Reduce the Pill Burden of Your PN Patients

    Bioavailability dosage chart for one Metanx® capsule

    Safe and Well Tolerated for Peripheral Neuropathy Care

    Clinical studies have shown that the ingredients in Metanx® are well-tolerated by patients, with a safety profile similar to placebo.6

    MetanxPRO Nerve Health™ / Metanx FC™ Comparison

    Diagram of biological mechanisms for nerve repair with Metanx products on a white background.
    Vitamins and supplements list for PRO and FC with key ingredients and their benefits on a white background